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As science continues its evolution, discoveries and technologies can act like a master key that open doors leading to novel advancements. Artificial intelligence is one such key, making innovations possible by solving complex problems, automating tasks and enabling research that would have been impossible, or very time-consuming, without it. Mohammad Hosseini But do we want to do research on all topics, and shall we try the AI master key on every door? To explore this question, let’s consider the use of AI by genomics experts as an example. In recent years, genomics experts have added unbelievable depth to what we know about the world and ourselves. For example, genetics researchers have revealed facts about when certain animals and plants were domesticated. In another example, researchers used DNA from 30,000-year-old permafrost to create fertile samples of a plant called narrow-leafed campion. Importantly, genetic engineering has facilitated extraordinary advances in the treatment of complicated conditions, such as sickle-cell anemia. Thanks to AI, we are witnessing a dramatic increase in the pace and scalability of genomic exploration. But given the risks and possible consequences of AI use in science, should we rush headlong into using AI in all kinds of projects? One relevant example is research on Neanderthals, our closest relatives, who lived about 40,000 years ago. Neanderthals have been studied for several years now through genetic investigation of their fossils and their DNA. Genetic engineering can potentially use ancient DNA and genome editing methods to re-create a Neanderthal or aspects of a Neanderthal’s genetics and physiology. To do this, scientists could start by figuring out the DNA sequence of a Neanderthal by comparing it with the DNA of modern humans, because they are closely related. Then, scientists could use the gene-editing tool known as CRISPR to swap out parts of human DNA with Neanderthal DNA. This process would require a lot of trial and error and might not succeed soon. But based on what we know about genetics, if something is possible, AI can help make it happen faster, cheaper and with less effort. Scientists are excited about these developments because they could facilitate new discoveries and open up many research opportunities in genetic research. With or without AI, research on Neanderthals will proceed. But the extraordinary power of AI could give the final push to these discoveries and facilitate this kind of resurrection. At that point, the scientific community must develop norms and guidelines about how to treat these resurrected beings with dispositions very similar to humans. We would need to carefully consider their rights and well-being almost in the same way as when humans are involved and not as research subjects or artifacts of scientific curiosity. These ethical issues are discussed in more detail in a new paper published in the journal Nature Machine Intelligence. A more holistic question to consider is: Should we prioritize the use of resource-intensive AI, researchers’ time and public funds to resurrect extinct beings? Or should we invest these resources into conserving species that are critically endangered today to prevent biodiversity from more degradation? Hosseini is an assistant professor in the Department of Preventive Medicine at Northwestern University’s Feinberg School of Medicine. He wrote this for The Chicago Tribune . Get opinion pieces, letters and editorials sent directly to your inbox weekly!
By HILLEL ITALIE NEW YORK (AP) — Even through a year of nonstop news about elections, climate change, protests and the price of eggs, there was still time to read books. Related Articles Books | Percival Everett, 2024 National Book Award winner, rereads one book often Books | Gift books for 2024: What to give, and what to receive, for all kinds of readers Books | Our critic’s picks: Best mystery fiction books of 2024 Books | 10 best books of 2024: The surprising reads that stuck Books | ‘We are time’s subjects’: Author Clock keeps track of the hours, one literary quotation at a time U.S. sales held steady according to Circana, which tracks around 85% of the print market, with many choosing the relief of romance, fantasy and romantasy. Some picked up Taylor Swift’s tie-in book to her blockbuster tour, while others sought out literary fiction, celebrity memoirs, political exposes and a close and painful look at a generation hooked on smartphones. Here are 10 notable books published in 2024, in no particular order. Asking about the year’s hottest reads would basically yield a list of the biggest hits in romantasy, the blend of fantasy and romance that has proved so irresistible fans were snapping up expensive “special editions” with decorative covers and sprayed edges. Of the 25 top sellers of 2024, as compiled by Circana, six were by romantasy favorite Sarah J. Maas, including “House of Flame and Shadow,” the third of her “Crescent City” series. Millions read her latest installment about Bryce Quinlan and Hunter Athalar and traced the ever-growing ties of “Maasverse,” the overlapping worlds of “Crescent City” and her other series, “Throne of Glass” and “A Court of Thorns and Roses.” If romantasy is for escape, other books demand we confront. In the bestselling “The Anxious Generation,” social psychologist Jonathan Haidt looks into studies finding that the mental health of young people began to deteriorate in the 2010s, after decades of progress. According to Haidt, the main culprit is right before us: digital screens that have drawn kids away from “play-based” to “phone-based” childhoods. Although some critics challenged his findings, “The Anxious Generation” became a talking point and a catchphrase. Admirers ranged from Oprah Winfrey to Arkansas Gov. Sarah Huckabee, who in a letter to state legislators advocated such “commonsense recommendations” from the book as banning phones in schools and keeping kids off social media until age 16. Bob Woodward books have been an election tradition for decades. “War,” the latest of his highly sourced Washington insider accounts, made news with its allegations that Donald Trump had been in frequent contact with Russian leader Vladimir Putin even while out of office and, while president, had sent Putin sophisticated COVID-19 test machines. Among Woodward’s other scoops: Putin seriously considered using nuclear weapons against Ukraine, and President Joe Biden blamed former President Barack Obama, under whom he served as vice president, for some of the problems with Russia. “Barack never took Putin seriously,” Woodward quoted Biden as saying. Former (and future) first lady Melania Trump, who gives few interviews and rarely discusses her private life, unexpectedly announced she was publishing a memoir: “Melania.” The publisher was unlikely for a former first lady — not one of the major New York houses, but Skyhorse, where authors include such controversial public figures as Woody Allen and Trump cabinet nominee Robert F. Kennedy Jr. And its success was at least a minor surprise. Melania Trump did little publicity for the book, and offered few revelations beyond posting a video expressing support for abortion rights — a break from one of the cornerstones of GOP policy. But “Melania” still sold hundreds of thousands of copies, many in the days following her husband’s election. Taylor Swift was more than a music story in 2024. Like “Melania,” the news about Taylor Swift’s self-published tie-in to her global tour isn’t so much the book itself, but that it exists. And how well it sold. As she did with the “Eras” concert film, Swift bypassed the established industry and worked directly with a distributor: Target offered “The Eras Tour Book” exclusively. According to Circana, the “Eras” book sold more than 800,000 copies just in its opening week, an astonishing number for a publication unavailable through Amazon.com and other traditional retailers. No new book in 2024 had a better debut. Midnight book parties are supposed to be for “Harry Potter” and other fantasy series, but this fall, more than 100 stores stayed open late to welcome one of the year’s literary events: Sally Rooney’s “Intermezzo.” The Irish author’s fourth novel centers on two brothers, their grief over the death of their father, their very different career paths and their very unsettled love lives. “Intermezzo” was also a book about chess: “You have to read a lot of opening theory — that’s the beginning of a game, the first moves,” one of the brothers explains. “And you’re learning all this for what? Just to get an okay position in the middle game and try to play some decent chess. Which most of the time I can’t do anyway.” Lisa Marie Presley had been working on a memoir at the time of her death , in 2023, and daughter Riley Keough had agreed to help her complete it. “From Here to the Great Unknown” is Lisa Marie’s account of her father, Elvis Presley, and the sagas of of her adult life, notably her marriage to Michael Jackson and the death of son Benjamin Keough. To the end, she was haunted by the loss of Elvis, just 42 when he collapsed and died at his Graceland home while young Lisa Marie was asleep. “She would listen to his music alone, if she was drunk, and cry,” Keough, during an interview with Winfrey, said of her mother. Meanwhile, Cher released the first of two planned memoirs titled “Cher” — no further introduction required. Covering her life from birth to the end of the 1970s, she focuses on her ill-fated marriage to Sonny Bono, remembering him as a gifted entertainer and businessman who helped her believe in herself while turning out to be unfaithful, erratic, controlling and so greedy that he kept all the couple’s earnings for himself. Unsure of whether to leave or stay, she consulted a very famous divorcee, Lucille Ball, who reportedly encouraged her: “F— him, you’re the one with the talent.” A trend in recent years is to take famous novels from the past, and remove words or passages that might offend modern readers; an edition of “The Adventures of Huckleberry Finn” cuts the racist language from Mark Twain’s original text. In the most celebrated literary work of 2024, Percival Everett found a different way to take on Twain’s classic — write it from the perspective of the enslaved Jim. “James,” winner of the National Book Award, is a recasting in many ways. Everett suggests to us that the real Jim was nothing like the deferential figure known to millions of readers, but a savvy and learned man who concealed his intelligence from the whites around him, and even from Twain himself. Salman Rushdie’s first National Book Award nomination was for a memoir he wished he had no reason to write. In “Knife,” he recounts in full detail the horrifying attempt on his life in 2022, when an attendee rushed the stage during a literary event in western New York and stabbed him repeatedly, leaving with him a blinded eye and lasting nerve damage, but with a spirit surprisingly intact. “If you had told me that this was going to happen and how would I deal with it, I would not have been very optimistic about my chances,” he told The Associated Press last spring. “I’m still myself, you know, and I don’t feel other than myself. But there’s a little iron in the soul, I think.”Cowboys set to host Bengals under open roof after falling debris thwarted that plan against Texans
Top Landing Spots for Free Agent Nick PivettaCOLLEGE PARK, Md. — Maryland quarterback Billy Edwards Jr. announced Thursday night he's decided to enter the transfer portal, meaning the Terrapins will likely have a new starter at the position for a second straight season. Edwards said on social media he's excited for the opportunities ahead. He threw for 2,881 yards in 11 games this season, his first as Maryland's No. 1 quarterback after Taulia Tagovailoa held down the position for four years. The Terrapins went 4-8 this season. Maryland has signed four-star quarterback Malik Washington, one of the highest-ranked recruits in the country at the position, as part of next year's class. Elsewhere, ESPN reported Boise State quarterback Malachi Nelson intends to enter the portal. Nelson has been a backup this season for the playoff-bound Broncos. Nelson was one of the top recruits nationally in 2023 and went to Southern California before transferring to Boise State.
Antitrust enforcers with the Federal Trade Commission have opened a wide-ranging investigation into Microsoft's business practices, starting a big legal project that an incoming Trump administration must take up or abandon. The FTC is investigating Microsoft's cloud computing business and related product lines such as artificial intelligence and cybersecurity, according to a person who was not authorized to discuss details of the investigation publicly and spoke to The Associated Press on condition of anonymity. Recommended Videos It's the latest action of more than three years of aggressive antitrust enforcement shepherded by FTC Chair Lina Khan, who was elevated to lead the agency by President Joe Biden after he came into office pledging tougher scrutiny of monopolistic behavior by Big Tech companies. Khan's FTC already lost one antitrust fight with Microsoft last year when a federal judge declined to block its $69 billion takeover of video game company Activision Blizzard. This case would go deeper into the core of Microsoft's business in a way the company hasn't experienced in the U.S. since its antitrust showdown with the Justice Department in the 1990s. Microsoft declined to comment. Bloomberg News first reported about the investigation last week. The case will only move forward if President-elect Donald Trump's choice to lead the FTC decides to continue the investigation and take it to court. Some analysts are expecting a lighter approach to the tech industry under Trump, though incoming Vice President JD Vance has praised Khan's work. A number of other tech-related antitrust matters are also in play, including the Department of Justice's investigation into chipmaker Nvidia and its push to break up Google — possibly spinning off the Chrome web browser — after a federal judge ruled Google maintained an illegal monopoly for the last decade.
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