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According to DelveInsight's analysis, the market for Down syndrome is anticipated to increase during the forecast period (2024–2034), owing to the launch of emerging therapies such as AEF0217, ACI-24.060, LEUCETTINIB-21, BUNTANETAP, and others and healthcare spending globally. LAS VEGAS , Nov. 26, 2024 /PRNewswire/ -- DelveInsight's Down's Syndrome Market Insights report includes a comprehensive understanding of current treatment practices, Down's syndrome emerging drugs, market share of individual therapies, and current and forecasted market size from 2020 to 2034, segmented into 7MM [ the United States , the EU4 ( Germany , France , Italy , and Spain ) and the United Kingdom , and Japan ]. Key Takeaways from the Down's Syndrome Market Report According to DelveInsight's analysis, the market size for Down's syndrome was found to be USD 241 million in the US in 2023. In 2023, the United States accounted for nearly 220K prevalent cases of Down's syndrome. The types of Down's syndrome include Trisomy 21, Robertsonian translocation, and Mosaicism. In 2023, among all types, Trisomy 21 accounted for the highest number of prevalent cases in the 7MM. Leading Down's syndrome companies such as AELIS FARMA, AC IMMUNE, PERHA PHARMACEUTICALS, ANNOVIS BIO, APHIOS THERAPEUTICS, and others are developing novel Down's syndrome drugs that can be available in the Down's syndrome market in the coming years. The promising Down's syndrome therapies in the pipeline include AEF0217, ACI-24.060, LEUCETTINIB-21, BUNTANETAP, APH-1104, and others. Discover which therapies are expected to grab the major Down's syndrome market share @ Down's Syndrome Market Report Down's Syndrome Overview Down's syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of an extra copy of chromosome 21. This chromosomal anomaly disrupts normal development, resulting in a range of physical and cognitive differences. The condition is primarily caused by random genetic mutations during the formation of reproductive cells or early embryonic development, though advanced maternal age increases the likelihood of having a child with Down's syndrome. People with Down's syndrome typically exhibit distinct facial features, such as a flattened face, almond-shaped eyes that slant upward, and a small nose. Other common symptoms include developmental delays, intellectual disabilities, and a variety of health issues like heart defects, respiratory and hearing problems, and a higher susceptibility to infections. Despite these challenges, many individuals with Down's syndrome lead fulfilling lives with appropriate support. Diagnosis of Down's syndrome can occur prenatally through screening and diagnostic tests, such as blood tests and ultrasounds in the first and second trimesters, or through more definitive tests like chorionic villus sampling (CVS) and amniocentesis. Postnatal diagnosis is typically confirmed by a physical examination and a karyotype analysis to identify the extra chromosome. Early diagnosis and intervention can help address developmental needs and improve the quality of life for individuals with Down's syndrome. Down's Syndrome Epidemiology Segmentation The Down's syndrome epidemiology section provides insights into the historical and current Down's syndrome patient pool and forecasted trends for the 7MM. It helps recognize the causes of current and forecasted patient trends by exploring numerous studies and views of key opinion leaders. The Down's syndrome market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM segmented into: Total Diagnosed Prevalent Cases of Down's Syndrome Gender-specific Diagnosed Prevalent Cases of Down's Syndrome Type-specific Diagnosed Prevalent Cases of Down's Syndrome Age-specific Diagnosed Prevalent Cases of Down's Syndrome Diagnosed Cases of Down's Syndrome by Clinical Manifestations Down's Syndrome Treatment Market There is no single treatment for Down's syndrome; instead, care plans are customized to address each person's unique physical and intellectual needs, emphasizing their strengths and accommodating their limitations. For some individuals, immediate surgery may be needed after birth to correct heart defects or long-term dietary modifications may be required for digestive concerns. Common interventions include assistive devices such as hearing aids, mobility aids, and adaptive technology to support learning and daily tasks. People with Down's syndrome often face an earlier and more pronounced cognitive decline than the general population. Treatments for Down syndrome-associated dementia (DSAD) may include medications like rivastigmine, galantamine, memantine, and donepezil, which inhibit acetylcholine breakdown, providing notable benefits. Seizure management for those with Down syndrome may involve anticonvulsants like carbamazepine and phenytoin, although these can exacerbate other Down syndrome-related issues. Respiratory problems are also common due to immune deficiencies and respiratory tract abnormalities, often requiring antibiotics or inhaled bronchodilators for effective management. Along with pharmacological treatments, non-pharmacological therapies such as physical, speech, occupational, and behavioral therapies play a vital role in the early development of children with Down syndrome, promoting independence and productivity. Physical therapy aims to improve motor skills, build muscle strength, and enhance posture and balance, laying the groundwork for key abilities. Speech-language therapy focuses on boosting communication skills and addressing physical challenges like low muscle tone to avoid long-term complications. Occupational therapy adapts daily tasks to suit the individual's abilities, teaching crucial skills such as eating, dressing, writing, and using a computer. Emotional and behavioral therapies tackle challenges like frustration from communication barriers, compulsive behaviors, and ADHD by identifying triggers and creating strategies to foster positive behaviors and reduce undesirable ones. To know more about Down's syndrome treatment guidelines, visit @ Down's Syndrome Management Down's Syndrome Pipeline Therapies and Key Companies AEF0217: AELIS FARMA ACI-24.060: AC IMMUNE LEUCETTINIB-21: PERHA PHARMACEUTICALS BUNTANETAP: ANNOVIS BIO APH-1104: APHIOS THERAPEUTICS Discover more about Down's syndrome drugs in development @ Down's Syndrome Clinical Trials Down's Syndrome Market Dynamics The Down's syndrome market dynamics are expected to change in the coming years. The prevalence of Down syndrome has increased with the rise in lifespan over the past three decades. This, along with the combination of several neurological features in Down syndrome patients—such as language impairment, cognition, learning, and memory—has sparked intense neurodevelopmental research. Studies in this area hold promise for improving clinical care and quality of life for individuals with Down syndrome and their families, as well as for assessing ways to enhance communication between parents and children. A thorough understanding of the factors affecting pharmacotherapy in Down syndrome could significantly contribute to better clinical outcomes for these individuals. Furthermore, potential therapies are being investigated for the treatment of Down's syndrome, and it is safe to predict that the treatment space will significantly impact the Down's syndrome market during the forecast period. Moreover, the anticipated introduction of emerging therapies with improved efficacy and a further improvement in the diagnosis rate are expected to drive the growth of the Down's syndrome market in the 7MM. However, several factors may impede the growth of the Down's syndrome market. Down syndrome presents unique challenges in clinical treatment, as there is currently no medical cure or approved products available in the market, complicating the treatment process. This complexity is compounded by the lack of appropriate, validated scales to measure progress or side effects in participants with learning disabilities, making it difficult to gauge treatment impact effectively. Furthermore, recruiting participants and their families is challenging, adding to the difficulties in conducting research. Down syndrome is also associated with numerous health problems and high healthcare costs , and individuals may require more intensive monitoring for adverse effects, adherence, and treatment efficacy when managing medications. Conducting clinical studies on the efficacy of psychotropic medications in individuals with Down syndrome is particularly challenging due to the unique language and communication characteristics of this population. Moreover, Down's syndrome treatment poses a significant economic burden and disrupts patients' overall well-being and QOL. Furthermore, Down's syndrome market growth may be offset by failures and discontinuation of emerging therapies , unaffordable pricing , market access and reimbursement issues , and a shortage of healthcare specialists . In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact Down's syndrome market growth. Down's Syndrome Market Report Metrics Details Study Period 2020–2034 Coverage 7MM [the United States, the EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan]. Down's Syndrome Market CAGR 3.81 % Down's Syndrome Market Size in the US in 2023 USD 241 Million Key Down's Syndrome Companies AELIS FARMA, AC IMMUNE, PERHA PHARMACEUTICALS, ANNOVIS BIO, APHIOS THERAPEUTICS, and others Key Pipeline Down's Syndrome Therapies AEF0217, ACI-24.060, LEUCETTINIB-21, BUNTANETAP, APH-1104, and others Scope of the Down's Syndrome Market Report Therapeutic Assessment: Down's Syndrome current marketed and emerging therapies Down's Syndrome Market Dynamics: Key Market Forecast Assumptions of Emerging Down's Syndrome Drugs and Market Outlook Competitive Intelligence Analysis: SWOT analysis and Market entry strategies Unmet Needs, KOL's views, Analyst's views, Down's Syndrome Market Access and Reimbursement Download the report to understand which factors are driving Down's syndrome market trends @ Down's Syndrome Market Trends Table of Contents 1 KEY INSIGHTS 2 REPORT INTRODUCTION 3 EXECUTIVE SUMMARY OF DOWN'S SYNDROME 4 DOWN'S SYNDROME MARKET OVERVIEW AT A GLANCE 4.1 MARKET SHARE BY THERAPIES (%) DISTRIBUTION OF DOWN'S SYNDROME IN 2020 IN THE 7MM 4.2 MARKET SHARE BY THERAPIES (%) DISTRIBUTION OF DOWN'S SYNDROME IN 2034 IN THE 7MM 5 KEY EVENTS 6 EPIDEMIOLOGY AND MARKET FORECAST METHODOLOGY 7 DOWN'S SYNDROME: DISEASE BACKGROUND AND OVERVIEW 7.1 INTRODUCTION 7.2 ETIOLOGY 7.3 TYPES OF DOWN'S SYNDROME 7.3.1 Trisomy 21 7.3.2 Translocation Down's syndrome 7.3.3 Mosaic Down's syndrome 7.4 CAUSES AND RISK FACTORS 7.5 COMPLICATIONS 7.6 OTHER HEALTH PROBLEMS 7.7 DIAGNOSIS 7.7.1 Screening Tests 7.7.2 Diagnostic Tests 7.8 TREATMENTS 7.8.1 Early Intervention and Educational Therapy 7.8.2 Treatment Therapies 7.8.3 Drugs and Supplements 7.8.4 Assistive Devices 8 CASE REPORTS 8.1 CASE STUDY: AN IPP TEAM HELPS 6-YEAR WITH DOWN'S SYNDROME IMPROVE COMMUNICATION SKILLS 9 EPIDEMIOLOGY AND PATIENT POPULATION 9.1 KEY FINDINGS 9.2 ASSUMPTIONS AND RATIONALE 9.3 TOTAL PREVALENT CASES OF DOWN'S SYNDROME IN THE 7MM 9.4 TYPE-SPECIFIC CASES OF DOWN'S SYNDROME IN THE 7MM 9.5 GENDER-SPECIFIC CASES OF DOWN'S SYNDROME IN THE 7MM 9.6 PREVALENT CASES OF DOWN'S SYNDROME BY CLINICAL MANIFESTATIONS IN THE 7MM 9.7 PREVALENT CASES OF DOWN'S SYNDROME BY AGE IN THE 7MM 9.8 THE UNITED STATES 9.8.1 Total Prevalent Cases of Down's Syndrome in the US 9.8.2 Type-specific Cases of Down's Syndrome in the US 9.8.3 Gender-specific Cases of Down's Syndrome in the US 9.8.4 Prevalent cases of Down's Syndrome by clinical manifestations in the US 9.8.5 Prevalent cases of Down's Syndrome by Age in the US 9.9 EU4 AND THE UK 9.9.1 Total Prevalent Cases of Down's syndrome in EU4 and the UK 9.9.2 Type-specific Cases of Down's syndrome in EU4 and the UK 9.9.3 Gender-specific Cases of Down's syndrome in EU4 and the UK 9.9.4 Prevalent cases of Down's syndrome by clinical manifestations in EU4 and the UK 9.9.5 Prevalent cases of Down's syndrome by Age in EU4 and the UK 9.10 JAPAN 9.10.1 Total Prevalent Cases of Down's syndrome in Japan 9.10.2 Type-specific Cases of Down's syndrome in Japan 9.10.3 Gender-specific Cases of Down's syndrome in Japan 9.10.4 Prevalent cases of Down's syndrome by clinical manifestations in Japan 9.10.5 Prevalent cases of Down's syndrome by Age in Japan 10 PATIENT JOURNEY 11 EMERGING DRUGS 11.1 KEY COMPETITORS 11.2 AEF0217: AELIS FARMA 11.2.1 Product Description 11.2.2 Other Developmental Activities 11.2.3 Clinical Development 11.2.3.1 Clinical Trials Information 11.2.4 Safety and Efficacy 11.3 ACI-24.060: AC IMMUNE 11.3.1 Product Description 11.3.2 Clinical Development 11.3.2.1 Clinical Trials Information 11.3.3 Safety and Efficacy 11.4 LEUCETTINIB-21: PERHA PHARMACEUTICALS 11.4.1 Product Description 11.4.2 Clinical Development 11.4.2.1 Clinical Trials Information 11.4.3 Other Developmental Activities 11.4.4 Safety and Efficacy 11.5 BUNTANETAP: ANNOVIS BIO 11.5.1 Product Description 11.5.2 Other Developmental Activities 11.5.3 Safety and Efficacy 11.6 APH-1104: APHIOS THERAPEUTICS 11.6.1 Product Description 11.6.2 Other Developmental Activities 12 DOWN'S SYNDROME: MARKET ANALYSIS 12.1 KEY FINDINGS 12.2 MARKET OUTLOOK 12.3 CONJOINT ANALYSIS 12.4 KEY MARKET FORECAST ASSUMPTIONS 12.5 TOTAL MARKET SIZE OF DOWN'S SYNDROME IN THE 7MM 12.6 UNITED STATES MARKET SIZE 12.6.1 Total Market Size of Down's Syndrome in the United States 12.6.2 Market Size of Down's Syndrome by Therapies in the United States 12.7 EU4 AND THE UK MARKET SIZE 12.7.1 Total Market Size of Down's Syndrome in EU4 and the UK 12.7.2 Market Size of Down's Syndrome by Therapies in EU4 and the UK 12.8 JAPAN MARKET SIZE 12.8.1 Total Market Size of Down's Syndrome in Japan 12.8.2 Market Size of Down's Syndrome by Therapies in Japan 13 UNMET NEEDS 14 SWOT ANALYSIS 15 MARKET ACCESS AND REIMBURSEMENT 15.1 UNITED STATES 15.1.1 Centre for Medicare & Medicaid Services (CMS) 15.2 EU4 AND THE UK 15.2.1 Germany 15.2.2 France 15.2.3 Italy 15.2.4 Spain 15.2.5 United Kingdom 15.3 JAPAN 15.3.1 MHLW 16 APPENDIX 16.1 BIBLIOGRAPHY 16.2 REPORT METHODOLOGY 17 DELVEINSIGHT CAPABILITIES 18 DISCLAIMER 19 ABOUT DELVEINSIGHT Related Reports Down's Syndrome Epidemiology Forecast Down's Syndrome Epidemiology Forecast – 2032 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology as well as the Down's syndrome epidemiology trends. Down's Syndrome Pipeline Down's Syndrome Pipeline Insight – 2024 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key Down's syndrome companies, including Alzheon, Inc, Connecta Therapeutics, among others. Alport Syndrome Market Alport Syndrome Market Insights, Epidemiology, and Market Forecast – 2034 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key Alport syndrome companies, including Eloxx Pharmaceuticals, Chinook Therapeutics (A Novartis company), Bayer, Calliditas Therapeutics, Evotec , among others. Alport Syndrome Pipeline Alport Syndrome Pipeline Insight – 2024 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key Alport syndrome companies, including Eloxx Pharmaceuticals, Inc., Chinook Therapeutic/Novartis, River 3 Renal Corp., Travere Therapeutics, Inc., Reata Pharmaceuticals, Inc., among others. About DelveInsight DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve . Contact Us Shruti Thakur info@delveinsight.com +14699457679 www.delveinsight.com Logo: https://mma.prnewswire.com/media/1082265/3528414/DelveInsight_Logo.jpgAmritsar: Various Panthic organisations, not aligned with Shiromani Akali Dal (SAD), have rallied to oppose the demand for excommunicating Narain Singh Chaura , who attempted to assassinate SAD president Sukhbir Singh Badal on Dec 4. A meeting of these Panthic factions was held here on Wednesday to discuss the Sikh sentiments, political situation in Punjab, and the honour and dignity of religious places. The group is expected to announce their next course of action on Thursday. It is learnt that Panthic leaders have urged the parallel acting Jathedar of Akal Takht, Bhai Dhian Singh Mand, to lead the movement and announce conferment of “Panth Rattan” title upon Chaura, in consideration of the broader sentiments of the Sikh community. When contacted, Bhai Jarnail Singh Sakhira, one of the Panthic leaders, confirmed that “something is being contemplated”, claiming that Mand will make the announcement of their next course of action and may announce to confer the “Panth Rattan” upon Chaura. “Chaura’s actions largely reflect the prevailing sentiment in the Panth and the deep dismay and utter disappointment felt by the people of Punjab, especially Sikhs, towards SAD. Many believed the SAD represented their interests, but over time, the party has become more focused on safeguarding the future of a select few, promoting nepotism, and benefiting a privileged group, while neglecting Panthic sentiments. This was made evident when SAD leaders themselves admitted to committing sins and mistakes during their tenure. Moreover, people are increasingly resentful of the lenient punishments given to those responsible,” said Sakhira. We also published the following articles recently Sukhbir Badal shooter Narain Chaura faces 21 cases, main accused in Burail jailbreak Former Khalistani militant Narain Singh Chaura, with a history of UAPA and Explosives Act charges, fired at ex-deputy CM Sukhbir Badal at Amritsar's Golden Temple. Linked to Babbar Khalsa and involved in the 2004 Burail jailbreak, Chaura, who authored "Khalistan Virudh Saazish," was reportedly on a mission against Badal and other leaders. Punjab police suspect hand of 2-3 people in attack on SAD leader Sukhbir Singh Badal Punjab police are investigating a deeper conspiracy in the attempted assassination of Sukhbir Singh Badal. Initial suspicions of a lone-wolf attack by Narain Singh Chaura are now evolving, with investigators probing the involvement of at least two other individuals, including Dharam Singh. Sikh factions rally behind Badal shooter, demand title for him Several Panthic groups in Amritsar are opposing the potential excommunication of Narain Singh Chaura, who attempted to assassinate SAD president Sukhbir Singh Badal at the Golden Temple. These groups, disillusioned with SAD, plan to honor Chaura, reflecting widespread Sikh resentment towards the party. Stay updated with the latest news on Times of India . Don't miss daily games like Crossword , Sudoku , and Mini Crossword .

American Airlines is rolling out tech that calls out passengers who try to board before their turn. Travelers can expect to see it in action at more than 100 airports this holiday season. The new tech also gives staff more info on passengers' connections and boarding groups. American Airlines is cracking down on passengers who try to sneak their way into an earlier boarding group. The airline is introducing new technology that helps gate agents catch overeager boarders at more than 100 airports across the country, the company said in a press release Wednesday. When a flyer tries to board their flight in an earlier boarding group than they're assigned, the gate agent's scanner will recognize the incorrect boarding group and notify them with a special two-tone sound. That alerts the agent to tell the passenger to wait their turn — and could also draw unwanted attention to the passenger. Boarding groups are designed to allow passengers with more expensive tickets, US military members, and certain airline status-holders to get on the plane earlier than those who haven't earned or bought these benefits. "We've heard from our customers that the ability to board with their assigned group is important to them because it's a benefit associated with their AAdvantage status or fare purchase," Julie Rath, a senior vice president at the airline, said in the company's press release. American has tested out this new software over the past month at airports in Tucson, Arizona; Albuquerque, New Mexico; and Washington, DC. The airline said that because it received a positive response from both customers and team members during this trial period, it decided to roll out the tech in time for the holiday travel season. Flyers can now expect the updates at non-hub airports in cities like Austin, Texas, and Atlanta. The company's hubs — which include airports in New York, Chicago, and Los Angeles — will be getting the tech in the coming months, the airline said. While the crackdown may be bad news for boarding group hoppers, it's likely great news for airline workers. Seasoned travelers, flight attendants, and gate staff say that people crowding the gate before boarding begins or trying to jump the boarding line is one of their biggest pet peeves. They even call some of these passengers "gate lice."The US Navy is to transform three, white elephant, stealth destroyers by fitting them with first-of-their-kind shipborne hypersonic weapons. The USS Zumwalt is at a Mississippi shipyard where workers have installed missile tubes that replace twin turrets from a gun system that was never activated because it was too expensive. Once the system is complete, the Zumwalt will provide a platform for conducting fast, precision strikes from greater distances, adding to the usefulness of the warship. “It was a costly blunder. But the Navy could take victory from the jaws of defeat here, and get some utility out of (the ships) by making them into a hypersonic platform,” said Bryan Clark, a defence analyst at the Hudson Institute. The US has had several types of hypersonic weapons in development for the past two decades, but recent tests by both Russia and China have added pressure to the US military to hasten their production. Hypersonic weapons travel beyond Mach 5, five times the speed of sound, with added manoeuvrability making them harder to shoot down. Last year, The Washington Post newspaper reported that among the documents leaked by former Massachusetts Air National Guard member Jack Teixeira was a defence department briefing that confirmed China had recently tested an intermediate-range hypersonic weapon called the DF-27. While the Pentagon had previously acknowledged the weapon’s development, it had not recognised its testing. One of the US programmes in development and planned for the Zumwalt is the Conventional Prompt Strike. It would launch like a ballistic missile and then release a hypersonic glide vehicle that would travel at speeds seven to eight times faster than the speed of sound before hitting the target. The weapon system is being developed jointly by the Navy and Army. Each of the three Zumwalt-class destroyers would be equipped with four missile tubes, each with three of the missiles for a total of 12 hypersonic weapons per ship. In choosing the Zumwalt, the Navy is attempting to add to the usefulness of a 7.5 billion US dollars (£5.9 billion) warship that is considered by critics to be an expensive mistake despite serving as a test platform for multiple innovations. The Zumwalt was envisioned as providing land-attack capability with an advanced gun system with rocket-assisted projectiles to open the way for Marines to charge ashore. But the system featuring 155mm guns hidden in stealthy turrets was cancelled because each of the rocket-assisted projectiles cost up to one million dollars (£790,000). Despite the stain on their reputation, the three Zumwalt-class destroyers: Zumwalt, Michael Monsoor and Lyndon B Johnson; remain the Navy’s most advanced surface warships in terms of new technologies. Those innovations include electric propulsion, an angular shape to minimise radar signature, an unconventional wave-piercing hull, automated fire and damage control and a composite deckhouse that hides radar and other sensors. The US is accelerating development because hypersonics have been identified as vital to US national security with “survivable and lethal capabilities”, said James Weber, principal director for hypersonics in the Office of the Assistant Secretary of Defense for Critical Technologies. “Fielding new capabilities that are based on hypersonic technologies is a priority for the defence department to sustain and strengthen our integrated deterrence, and to build enduring advantages,” he said.

Laura Woods shows off blossoming baby bump at Wembley as ITV host presents England Lionesses draw with United StatesBy joining forces, Amazon and Perplexity aim to push the boundaries of what AI can achieve. One key area of focus for this partnership is improving the conversational capabilities of virtual assistants like Alexa. The goal is to create more engaging and human-like interactions that feel natural and intuitive to users.November 22, 2024 This article has been reviewed according to Science X's editorial process and policies . Editors have highlightedthe following attributes while ensuring the content's credibility: fact-checked peer-reviewed publication trusted source proofread by Francisco Tutella, Pennsylvania State University Spanish explorers may have brought the first peach pits to North America, but Indigenous communities helped the ubiquitous summer fruit really take root, according to a study led by a researcher at Penn State. The study, published in Nature Communications , shows that Indigenous political and social networks and land use practices played key roles in the peach's adoption and dispersal across the continent, according to the researchers. "Peaches need a lot of care by people to be productive. They need to be planted in appropriate places with a lot of sunlight and the right soil drainage, and they need to be pruned," said Jacob Holland-Lulewicz, first author and assistant professor of anthropology at Penn State. "For a long time, the narrative was that the Spanish introduced peaches and then peaches spread very quickly. The reality is way more complicated. How quickly peaches spread is very much a product of Indigenous networks and land management." The researchers analyzed historical documents that mentioned peaches, such as the travel writings of French missionary explorer Jacques Marquette and English merchant Jonathan Dickinson. They also employed radiocarbon dating —a method that measures the decay of radioactive carbon-14 atoms in organic material —to determine the approximate ages of peach pits and other organic samples, like carbonized tree wood, from 28 archaeological sites and two regional locales where archaeologists previously recovered preserved peach pits. The sites were located in the Carolinas, Georgia, Florida, Alabama, Tennessee and Arkansas. The team found that peaches were likely widespread across Indigenous settlements in the interior southeast as early as the year 1620, roughly 100 years after the earliest Spanish expeditions in Florida and in Georgia's Oconee Valley. The timing suggests that early Spanish settlements becoming important trade nodes within existing Indigenous networks created the necessary conditions for the spread of peaches, according to Holland-Lulewicz. "Many narratives talk about the Spanish, or Europeans generally, arriving and then you see instantaneous changes to Indigenous histories and the spread of materials, but those initial interactions didn't cause major changes," he said. "It's not until Spanish networks and Indigenous networks become entangled 100 years later that we have the necessary conditions for the spread of peaches." The team also identified what are possibly the earliest peaches in North America at a Muskogean farmstead in the Oconee Valley. In the 1990s, the late Penn State archaeologist James Hatch recovered peach pits from the bottom of post holes that once housed support structures for the farmstead's house. The researchers radiocarbon dated charcoal, nuts and corn kernels from these post holes and found that occupation at the site began between 1520 and 1550 and ended between 1530 and 1570. This timing suggests that peaches had spread to the interior southeast possibly decades before the founding of St. Augustine in 1565, according to the researchers. Discover the latest in science, tech, and space with over 100,000 subscribers who rely on Phys.org for daily insights. Sign up for our free newsletter and get updates on breakthroughs, innovations, and research that matter— daily or weekly . "Understanding the path that the introduction of species, such as peach trees, took through colonization and the role that Indigenous people and their long-term relationship with the environment played in shaping these histories demonstrates the importance of these events, people and processes to what becomes a broader American history," said co-author Victor Thompson, Distinguished Research Professor of archaeology at the University of Georgia (UGA) and executive director of the Georgia Museum of Natural History. "Further, the fact that all of this work took place on museum specimens underscores the importance of maintaining these collections for future study." Indigenous peoples not only adopted the peach but selectively bred new varieties outnumbering the varieties found in Europe even at this early time, Holland-Lulewicz said. "When Europeans started to move through and into the interior of the continent in the mid- to late 1600s, they noted that there were way more varieties of peaches being grown by Indigenous peoples than there were in Europe," he said, explaining that the fruit had become an important aspect of Indigenous culture. "At this time, Europeans are noting really dense peach orchards around Indigenous towns, but some of these towns and people had never previously interacted with or even heard of Europeans. In fact, there are records of Indigenous peoples describing peaches as an Indigenous fruit." The fruit had become so integral to Indigenous history and culture that when the ancestors of the modern-day Muscogee (Creek) Nation were forcibly removed from Georgia and Alabama during the 1800s, they took peaches with them. "There are Muscogee (Creek) peoples today who grow peaches as heritage crops," Holland-Lulewicz said. "The act of growing and caring for those peaches is an important cultural practice. These were the first peaches introduced in the 1500s and 1600s that were then carried halfway across the continent and continue to be grown today." More information: Jacob Holland-Lulewicz et al, The initial spread of peaches across eastern North America was structured by Indigenous communities and ecologies, Nature Communications (2024). DOI: 10.1038/s41467-024-52597-8 Journal information: Nature Communications Provided by Pennsylvania State University

Virgo Daily Horoscope Today, November 27, 2024 predicts a vacation soonAs the last player standing, this individual embodies the spirit of the LGBT community – one that refuses to be silenced or dismissed. Their journey through "LGBT Warrior: A Solo Journey" is not just a quest for victory, but a testament to the power of individuality and resilience. In a world where conformity often reigns supreme, this lone warrior stands as a beacon of hope and inspiration for those who dare to defy the norms.

Furthermore, the success of the trade-in subsidy program reflects a growing trend among consumers towards responsible and sustainable consumption practices. By choosing to participate in the initiative, car owners are not only benefiting from financial incentives but also contributing to efforts to reduce carbon emissions and promote environmental sustainability.The best Lululemon Cyber Monday deals include Align leggings, Scuba hoodies and belt bags under $100More than 6000 prisoners escape high-security prison in Mozambique

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WASHINGTON — Only about 2 in 10 Americans approve of President Joe Biden's decision to pardon his son Hunter after earlier promising he would do no such thing, according to a poll from The Associated Press-NORC Center for Public Affairs Research. That displeasure tracks with the bipartisan uproar in Washington that ignited over the president's about-face. The survey found that a relatively small share of Americans "strongly" or "somewhat" approve of the pardon, which came after the younger Biden was convicted on gun and tax charges. About half said they "strongly" or "somewhat" disapprove, and about 2 in 10 neither approve nor disapprove. The Democratic president said repeatedly that he would not use his pardon power for the benefit of his family, and the White House continued to insist, even after Republican Donald Trump's election win in November, that Biden's position had not changed — until it suddenly did. People are also reading... Nebraska transportation director: Expressway system won't be done until 2042 At the courthouse, Dec. 7, 2024 Camper total loss after fire north of Beatrice 27-year-old Beatrice man sentenced for May assault Stabler scores 22 in Lady O's season opening win BPS receives a "good" classification Holiday lights travel through downtown Beatrice for annual parade Orangemen open season with win over Nebraska City P.E.O. sponsors Holiday Tour of Homes Missouri man sentenced for attempted sexual assault At the courthouse, Nov. 30, 2024 Community Players open holiday play Amie Just: This recruiting class marks the beginning of a new era — one without walk-ons Traffic enforcement campaigns net safety reminders, citations Lonnie Meyer Hunter Biden leaves federal court Sept. 5 in Los Angeles after pleading guilty to federal tax charges. "I know it's not right to believe politicians as far as what they say compared to what they do, but he did explicitly say, 'I will not pardon my son,'" said Peter Prestia, a 59-year-old Republican from Woodland Park, New Jersey, just west of New York City, who said he strongly disagreed with the move. "So, it's just the fact that he went back on his word." In issuing a pardon Dec. 1, Biden argued that the Justice Department had presided over a "miscarriage of justice" in prosecuting his son. The president used some of the same kind of language that Trump does to describe the criminal cases against him and his other legal predicaments. White House press secretary Karine Jean-Pierre said it was a decision that Biden struggled with but came to shortly before he made the announcement, "because of how politically infected these cases were" as well as "what his political opponents were trying to do." The poll found that about 4 in 10 Democrats approve of the pardon, while about 3 in 10 disapprove and about one-quarter did not have an opinion or did not know enough to say. The vast majority of Republicans and about half of independents had a negative opinion. President Joe Biden and son Hunter Biden walk Nov. 29 in downtown Nantucket Mass. For some, it was easy to see family taking priority over politics. "Do you have kids?" asked Robert Jenkins, a 63-year-old Democrat who runs a lumber yard and gas station in Gallipolis, Ohio. "You're gonna leave office and not pardon your kid? I mean, it's a no-brainer to me." But Prestia, who is semiretired from working for a digital marketing conglomerate, said Biden would have been better off not making promises. "He does have that right to pardon anybody he wants. But he just should have kept his mouth shut, and he did it because it was before the election, so it's just a bold-faced lie," Prestia said. Despite the unpopularity of his decision, the president's approval rating has not shifted meaningfully since before his party lost the White House to Trump. About 4 in 10 Americans "somewhat" or "strongly" approve of the way Biden is handling his job as president, which is about where his approval rating stood in AP-NORC polls since January 2022. Still, the pardon keeps creating political shock waves, with Republicans, and even some top Democrats, decrying it. Older adults are more likely than younger ones to approve of Biden's pardoning his son, according to the poll, though their support is not especially strong. About one-third of those ages 60 and older approve, compared with about 2 in 10 adults under 60. The age divide is driven partially by the fact that younger adults are more likely than older ones to say they neither approve nor disapprove of the pardon or that they do not know enough to say. President Joe Biden walks with his son Hunter Biden on July 26 as he heads toward Marine One on the South Lawn of the White House in Washington. About 6 in 10 white adults disapprove of the pardon, compared with slightly less than half of Hispanic adults and about 3 in 10 Black adults. Relatively large shares of Black and Hispanic Americans — about 3 in 10 — were neutral, the poll found. "Don't say you're gonna do something and then fall back," said Trinell Champ, 43, a Democrat from Nederland, Texas, who works in the home health industry and said she disapproved of the pardon. "At the end of the day, all you have is your word." Champ, who is Black, voted for Democratic Vice President Kamala Harris over Trump. "I just had my hopes up for her, but I wasn't 100% positive," she said. Champ also said she does not approve of Biden's handling of the presidency and thinks the country is on the wrong track. "While he was in office, I felt like I really didn't see a lot of changes," she said. "I just felt like everything just kind of stayed the same," Champ said. Overall, though, the pardon did not appear to be a driving factor in many Americans' assessment of Biden's job performance. The share of Black Americans who approve of the way he is handling his job as president did fall slightly since October, but it is hard to assess what role the pardon may have played. Photos: Joe Biden through the years Joe Biden, 1972 Sen. Joe Biden (D-Del.) carries both of his sons, Joseph R. III, left, and Robert H., during an appearance at the Democratic state convention last summer, 1972. At center is his wife Neilia Biden, who was killed in an auto crash, Dec. 20, 1972. With them are Governor-elect Sherman W. Tribbitt and his wife, Jeanne. (AP Photo) Joe Biden, 1972 Joseph Biden, the newly-elected Democratic Senator from Delaware, is shown in Washington, Dec. 12, 1972. (AP Photo/Henry Griffin) Joe Biden, 1972 1972 - Is first elected to the Senate at age 29, defeating Republican Senator J. Caleb Boggs. Wins re-election in 1978, 1984, 1990, 1996 and 2002. The newly-elected Democratic senator from Delaware, Joe Biden, is shown, Dec. 13, 1972. Joe Biden, 1972 Sen. Joe Biden (D-Del.) kisses the cheek of an unidentified friend who offered consoling words after a memorial service in Wilmington, Del., Dec. 22, 1972, for Biden's wife Neilia, their 13-month-old daughter Naomi Christina, who perished in a car-truck crash. Biden's two sons were hospitalized with serious injuries. (AP Photo/Bill Ingraham) Joe Biden, 1973 December 18, 1972 - While Christmas shopping, Biden's first wife, Neilia Hunter Biden, and daughter, Naomi Biden, are killed in a car accident. His sons are badly injured, but survive. January 5, 1973 - Is sworn in as US senator of Delaware at son Beau Biden's bedside in the hospital. In this Jan. 5, 1973 file photo, four-year-old Beau Biden, foreground, plays near his father, Joe Biden, center, being sworn in as the U.S. senator from Delaware, by Senate Secretary Frank Valeo, left, in ceremonies in a Wilmington hospital. Beau was injured in an accident that killed his mother and sister in December 1972. Biden's father, Robert Hunter, holds the Bible. (AP Photo/File) Joe Biden, 1987 1987-1995 - Chairman of the Senate Committee on the Judiciary. Sen. Joe Biden (D-Del.), chairman of the Senate Judiciary Committee, rubs his temples while speaking during confirmation hearings for Supreme Court nominee Robert H. Bork, Sept. 17, 1987, on Capitol Hill. (AP Photo/John Duricka) Joe Biden, 1987 June 9, 1987 - Enters the 1988 presidential race, but drops out three months later following reports of plagiarism and false claims about his academic record. Sen. Joe Biden (D-Del.) waves from his train as he leaves Wilmington, Del., after announcing his candidacy for president, June 9, 1987. At right, son Beau carries daughter; to Biden's right is his wife Jill and son Hunter. (AP Photo/George Widman) Joe Biden, 1988 February 1988 - Undergoes surgery to repair an aneurysm in an artery that supplies blood to the brain. Sen. Joseph Biden (D-Del.), wearing a University of Delaware baseball cap, leaves Walter Reed Army Hospital accompanied by his son Hunter Biden, Thursday, March 24, 1988, Washington, D.C. Biden had been in the hospital for 11 days so that surgeons could implant a small umbrella-like filter in a vein to prevent blood clots from reaching his lungs. (AP Photo/Adele Starr) Joe Biden, 1991 In this Oct. 12, 1991 file photo Senate Judiciary Committee Chairman Joe Biden, D-Del., points angrily at Clarence Thomas during comments at the end of hearings on Thomas' nomination to the Supreme Court on Capitol Hill. Sen. Edward Kennedy, D-Mass. looks on at right. (AP Photo/Greg Gibson, File) Joe Biden, 1993 January 20, 1990 - Introduces a bill that becomes the Violence Against Women Act (VAWA). The act addresses sexual assault and domestic violence. It is signed into law by President Bill Clinton in 1994. Sen. Joe Biden (D-Del.), left, stands behind a flag as Sen. Barbara Boxer (D-Calif.), second from right, along with other congresswomen meet reporters on Capitol Hill, Feb. 24, 1993, to discuss the Violence Against Women Act. From left are: Sen. Biden; Rep. Louise Slaughter (D-N.Y.); Rep. Pat Schroeder (D-Colo); Sen. Boxer; and Rep. Constance Morella of Maryland. (AP Photo/Barry Thumma) Joe Biden, 1993 In this April 9, 1993, file photo Sen. Joe Biden, D-Del. stands in front of a Danish armored personnel carrier at the UN-controlled Sarajevo Airport, making a statement about his trip to the besieged Bosnian capital. (AP Photo/Michael Stravato, File) Joe Biden, 2003 Sen. Joseph Biden, D-Del., ranking Democrat on the Senate Foreign Relations Committee, meets reporters on Capitol Hill Thursday, Oct. 16, 2003 to discuss the United Nations-Iraq vote. (AP Photo/Terry Ashe) Joe Biden, 2007 Democratic presidential hopeful, and Senate Foreign Relations Committee Chairman Sen. Joseph Biden, D-Del., presides over a hearing of the committee on Capitol Hill in Washington, Thursday, Feb. 1, 2007 to discuss the remaining options in Iraq. (AP Photo/Dennis Cook) Joe Biden, 2007 Democratic presidential hopeful U.S. Sen. Joseph Biden D-Del., smiles during the Iowa Federation of Labor, AFL-CIO Presidential Forum Wednesday, Aug. 15, 2007, in Waterloo, Iowa. (AP Photo/M. Spencer Green) Joe Biden, 2007 January 31, 2007 - Files a statement of candidacy with the Federal Elections Commission to run for president. August 1, 2007 - His memoir, "Promises to Keep: On Life and Politics," is published. Sen. Joe Biden, D-Del., left, listens as Sen. Barack Obama, D-Ill., responds to a question during the first Democratic presidential primary debate of the 2008 election hosted by the South Carolina State University in Orangeburg, SC., Thursday, April 26, 2007. At right is Sen. Hillary Rodham Clinton, D-NY. (AP Photo/J. Scott Applewhite) Joe Biden, 2008 Sen. Joseph Biden, D-Del., speaks at a Caucus night rally in Des Moines, Iowa, Thursday, Jan. 3, 2008. Biden abandoned his bid for the Democratic presidential nomination Thursday after a poor showing in the state's caucuses. (AP Photo/Jeff Chiu) Joe Biden, 2008 In this Jan. 3, 2008, file photo, Democratic presidential hopeful, Sen. Joe Biden, D-Del., rests his head on the shoulder of his wife, Jill, as they stand in a hallway awaiting his introductions for a rally at the UAW Hall in Dubuque, Iowa on the day of the Iowa caucus in Dubuque, Iowa. (AP Photo/Mark Hirsch, File) Joe Biden, 2008 August 23, 2008 - Is named the vice-presidential running mate of Barack Obama. In this Aug. 23, 2008 file photo, Democratic presidential candidate Sen. Barack Obama D-Ill., and his vice presidential running mate Sen. Joe Biden, D-Del., appear together in Springfield, Ill. (AP Photo/M. Spencer Green, file) Joe Biden, 2008 In this Sept. 16, 2008 file photo, then Democratic vice presidential candidate Sen. Joe Biden, D-Del. arrives by Amtrak in Wilmington, Del., (AP Photo/Gerald Herbert, File) Joe Biden, 2008 In this Oct. 2,2008 file photo, Democratic vice presidential candidate Sen. Joe Biden, D-Del., left, and Republican vice presidential candidate Alaska Gov. Sarah Palin face off during the vice presidential debate at Washington University in St. Louis. (AP Photo/Tom Gannam, File) Joe Biden, 2008 November 4, 2008 - Is elected vice president of the United States. President-elect Barack Obama, left, and Vice President-elect Joe Biden wave to the crowd after Obama's acceptance speech at his election night party at Grant Park in Chicago before giving his acceptance speech Tuesday night, Nov. 4, 2008. (AP Photo/Morry Gash) Joe Biden, 2009 January 20, 2009 - Is sworn in as vice president of the United States. Vice President Joe Biden, left, with his wife Jill at his side, taking the oath of office from Justice John Paul Stevens at the U.S. Capitol in Washington, Tuesday, Jan. 20, 2009. (AP Photo/Elise Amendola) Joe Biden, 2009 February 7, 2009 - Delivers his first major speech as vice president at a security conference in Germany. US Vice President Joe Biden addresses the participants of the International Conference on Security Policy, Sicherheitskonferenz, at the hotel "Bayerischer Hof" in Munich, southern Germany, on Saturday, Feb. 7, 2009. Joe Biden, 2010 September 1, 2010 - Presides over a ceremony in Iraq to formally mark the end of the US combat mission in Iraq. US Vice President Joe Biden, left, US Secretary of Defense Robert Gates, center, and Chairman of the Joint Chiefs Admiral Mike Mullen, right, stand while the US National Anthem is played during the United States Forces-Iraq change of command ceremony in Baghdad on Wednesday Sept. 1, 2010, as a new US military mission in Iraq was launched ending seven years of combat. (AP Photo/Jim Watson Pool) Joe Biden, 2012 November 6, 2012 - Obama and Biden are reelected, defeating Mitt Romney and Paul Ryan. Vice President Joe Biden exits with his wife Jill Biden after voting at Alexis I. duPont High School, Tuesday, Nov. 6, 2012, in Greenville, Del. (AP Photo/Matt Rourke) Joe Biden, 2013 Vice President Joe Biden, with his wife Jill Biden, center, holding the Biden Family Bible, shakes hands with Supreme Court Justice Sonia Sotomayor after taking the oath of office during an official ceremony at the Naval Observatory, Sunday, Jan. 20, 2013, in Washington. (AP Photo/Carolyn Kaster) Joe Biden, 2014 October 2, 2014 - Speaking at the John F. Kennedy School of Government at Harvard University, Biden tells attendees that ISIS has been inadvertently strengthened by actions taken by Turkey, the UAE and other Middle Eastern allies to help opposition groups fighting against Syrian President Bashar al-Assad. In this Thursday, Oct. 2, 2014 file photo, Vice President Joe Biden speaks to students, faculty and staff at Harvard University in Cambridge, Mass. Biden is due to headline a Democratic campaign rally in Las Vegas, with a downtown appearance Monday, Oct. 6, 2014, to talk about raising the minimum wage. (AP Photo/Winslow Townson,File) Joe Biden, 2015 May 30, 2015 - Biden's eldest son, Beau Biden, passes away from brain cancer at age 46. In this June 6, 2015 file photo, Vice President Joe Biden, accompanied by his family, holds his hand over his heart as he watches an honor guard carry a casket containing the remains of his son, former Delaware Attorney General Beau Biden, into St. Anthony of Padua Roman Catholic Church in Wilmington, Del. for funeral services. Beau Biden died of brain cancer May 30 at age 46. (AP Photo/Patrick Semansky) Joe Biden, 2015 October 21, 2015 - Says he will not seek the presidency, announcing that the window for a successful campaign "has closed." December 6, 2016 - Doesn't rule out running for president in 2020, saying "I'm not committing not to run. I'm not committing to anything. I learned a long time ago fate has a strange way of intervening." President Barack Obama hugs Vice President Joe Biden as Biden waves at the end Biden's announcement in the Rose Garden of the White House in Washington, Wednesday, Oct. 21, 2015, that he will not run for the presidential nomination. Jill Biden is at right. (AP Photo/Jacquelyn Martin) Joe Biden, 2017 Vice President Joe Biden pauses between mock swearing in ceremonies in the Old Senate Chamber on Capitol Hill in Washington, Tuesday, Jan. 3, 2017, as the 115th Congress begins. (AP Photo/Alex Brandon) Joe Biden, 2017 January 12, 2017 - Obama surprises Biden by presenting him the Presidential Medal of Freedom, the nation's highest civilian honor, during a White House ceremony. President Barack Obama presents Vice President Joe Biden with the Presidential Medal of Freedom during a ceremony in the State Dining Room of the White House in Washington, Thursday, Jan. 12, 2017. (AP Photo/Susan Walsh) Joe Biden, 2017 February 1, 2017 - Biden and his wife, Jill Biden, launch the Biden Foundation, an organization that will work on seven issues: foreign policy; Biden's cancer initiative; community colleges and military families; protecting children; equality; ending violence against women; and strengthening the middle class. February 7, 2017 - Is named the Benjamin Franklin presidential practice professor at the University of Pennsylvania, where he will lead the Penn Biden Center for Diplomacy and Global Engagement. He will also serve as the founding chair of the University of Delaware's Biden Institute, the university announces. March 1, 2017 - Biden receives the Congressional Patriot Award from the Bipartisan Policy Center. He receives the honor in recognition of his work crafting bipartisan legislation with Republicans and Democrats. Former Vice President Joe Biden tucks notes into his jacket after speaking at an event to formally launch the Biden Institute, a research and policy center focused on domestic issues at the University of Delaware, in Newark, Del., Monday, March 13, 2017. (AP Photo/Patrick Semansky) Joe Biden, 2019 In this March 26, 2019, file photo, former Vice President Joe Biden speaks at the Biden Courage Awards in New York. (AP Photo/Frank Franklin II, File) Joe Biden, 2019 April 25, 2019 - Announces he is running for president in a campaign video posted to social media. Hours later, the Biden Foundation board chair, Ted Kaufman, announces the immediate suspension of all the organization's operations. Former Vice President and Democratic presidential candidate Joe Biden arrives at the Wilmington train station Thursday April 25, 2019 in Wilmington, Delaware. Biden announced his candidacy for president via video on Thursday morning. (AP Photo/Matt Slocum) Joe Biden, 2019 In this June 6, 2019, file photo, Democratic presidential candidate former Vice President Joe Biden speaks during the "I Will Vote" fundraising gala in Atlanta. Biden shifted to oppose longstanding restrictions on federal funding of abortion during his remarks. (AP Photo/John Bazemore, File) Joe Biden, 2020 Democratic presidential candidate, former Vice President Joe Biden signs a copy of his book "Promise Me, Dad" at a campaign rally at Modern Woodmen Park, Sunday, Jan. 5, 2020, in Davenport, Iowa. (AP Photo/Andrew Harnik) Joe Biden, 2020 Democratic presidential candidate former Vice President Joe Biden speaks at a primary night election rally in Columbia, S.C., Saturday, Feb. 29, 2020 after winning the South Carolina primary. (AP Photo/Gerald Herbert) Joe Biden, 2020 Democratic presidential candidate former Vice President Joe Biden speaks at a primary night election rally in Columbia, S.C., Saturday, Feb. 29, 2020, after winning the South Carolina primary. (AP Photo/Matt Rourke) Joe Biden, 2020 Democratic presidential candidate former Vice President Joe Biden speaks at a primary election night campaign rally Tuesday, March 3, 2020, in Los Angeles. (AP Photo/Chris Carlson) Joe Biden, 2020 August 20, 2020: Joe Biden accepts the Democratic nomination for president Democratic presidential candidate former Vice President Joe Biden speaks during the fourth day of the Democratic National Convention, Thursday, Aug. 20, 2020, at the Chase Center in Wilmington, Del. (AP Photo/Andrew Harnik) Joe Biden, 2020 Democratic presidential candidate former Vice President Joe Biden, with Democratic vice presidential candidate Sen. Kamala Harris, D-Calif., raise their arms up as fireworks go off in the background during the fourth day of the Democratic National Convention, Thursday, Aug. 20, 2020, at the Chase Center in Wilmington, Del. Looking on are Jill Biden, far left, and Harris' husband Doug Emhoff, far right. (AP Photo/Andrew Harnik) Joe Biden, 2020 President Donald Trump, left, and Democratic presidential candidate former Vice President Joe Biden, right, with moderator Chris Wallace, center, of Fox News during the first presidential debate Tuesday, Sept. 29, 2020, at Case Western University and Cleveland Clinic, in Cleveland, Ohio. (AP Photo/Patrick Semansky) Joe Biden, 2020 Democratic presidential candidate former Vice President Joe Biden, right, and former President Barack Obama greet each other with an air elbow bump, at the conclusion of rally at Northwestern High School in Flint, Mich., Saturday, Oct. 31, 2020. (AP Photo/Andrew Harnik) Joe Biden, 2020 Democratic presidential candidate former Vice President Joe Biden arrives to speak at a rally at Belle Isle Casino in Detroit, Mich., Saturday, Oct. 31, 2020, which former President Barack Obama also attended. (AP Photo/Andrew Harnik) Joe Biden, 2020 President-elect Joe Biden gestures on stage after speaking, Saturday, Nov. 7, 2020, in Wilmington, Del. (AP Photo/Andrew Harnik, Pool) Joe Biden, 2020 FILE - In this Saturday, Nov. 7, 2020, file photo, from left, Doug Emhoff, husband of Vice President-elect Kamala Harris, Harris, President-elect Joe Biden and his wife, Jill Biden, stand on stage together, in Wilmington, Del. The theme for Biden’s inauguration will be “America United." Unity is an issue that’s long been a central focus for Biden but one that’s taken on added weight in the wake of the violence at the U.S. Capitol. (AP Photo/Andrew Harnik, Pool, File) Joe Biden, 2020 President-elect Joe Biden announces his climate and energy team nominees and appointees at The Queen Theater in Wilmington Del., Saturday, Dec. 19, 2020. (AP Photo/Carolyn Kaster) Joe Biden, 2021 President Joe Biden speaks about his domestic agenda from the East Room of the White House in Washington on Oct. 28, 2021. (AP Photo/Susan Walsh) Joe Biden, 2021 U.S. President Joe Biden, left, shakes hands with Pope Francis as they meet at the Vatican on Oct. 29, 2021. (Vatican Media via AP) Joe Biden, 2021 President Joe Biden removes his face mask as he arrives in the East Room of the White House to speak about the evacuation of American citizens, their families, special immigrant visa applicants and vulnerable Afghans on Aug. 20, 2021, in Washington. (AP Photo/Manuel Balce Ceneta) Joe Biden, 2022 Cherelle Griner, wife of WNBA star Brittney Griner, speaks after President Joe Biden announced Brittney Griner's release in a prisoner swap with Russia on Dec. 8, 2022, in the Roosevelt Room of the White House in Washington. Also attending are Secretary of State Antony Blinken, left, and Vice President Kamala Harris. Joe Biden, 2022 President Joe Biden holds the microphone to Chocolate, the national Thanksgiving turkey, during a pardoning ceremony Nov. 21, 2022, at the White House in Washington. Joe Biden, 2022 President Joe Biden holds an Atlanta Braves jersey during an event celebrating the Major League Baseball 2021 World Series champion Atlanta Braves in the East Room of the White House on Sept. 26, 2022, in Washington. Joe Biden, 2022 President Joe Biden receives his COVID-19 booster from a member of the White House medical unit during an event in the South Court Auditorium on the White House campus on Oct. 25, 2022, in Washington. Joe Biden, 2022 President Joe Biden and first lady Jill Biden arrive to give treats to trick-or-treaters on the South Lawn of the White House, on Halloween on Oct. 31, 2022, in Washington. Joe Biden, 2022 U.S. President Joe Biden, left, talks with Indonesian President Joko Widodo during their bilateral meeting ahead of the G20 Summit in Nusa Dua, Bali, Indonesia, on Nov. 14, 2022. Joe Biden, 2022 U.S. President Joe Biden, right, and Chinese President Xi Jinping shake hands before a meeting on the sidelines of the G20 summit meeting Nov. 14, 2022, in Bali, Indonesia. Joe Biden, 2023 President Joe Biden is greeted by Israeli Prime Minister Benjamin Netanyahu after arriving at Ben Gurion International Airport on Oct. 18, 2023, in Tel Aviv. Joe Biden, 2023 President Joe Biden speaks from the Oval Office of the White House on Oct. 19, 2023, in Washington, about the war in Israel and Ukraine. Joe Biden, 2023 President Joe Biden arrives to speak at the Amtrak Bear Maintenance Facility on Nov. 6, 2023, in Bear, Del. Joe Biden, 2023 President Joe Biden, accompanied by Office of Management and Budget director Shalanda Young, left, and Women's Alzheimer's Movement founder Maria Shriver, right, gives first lady Jill Biden a kiss after giving her the pen he used to sign a presidential memorandum that will establish the first-ever White House Initiative on Women's Health Research in the Oval Office of the White House on Nov. 13, 2023, in Washington. Joe Biden, 2023 President Joe Biden pauses as he speaks to reporters in Nantucket, Mass. on Nov. 26, 2023, about hostages freed by Hamas in a third set of releases under a four-day cease-fire deal between Israel and Hamas. Joe Biden, 2023 President Joe Biden shakes hands with Ukrainian President Volodymyr Zelenskyy as they meet in the Oval Office of the White House on Dec. 12, 2023, in Washington. Joe Biden, 2023 President Joe Biden and Ukrainian President Volodymyr Zelenskyy depart a news conference in the Indian Treaty Room in the Eisenhower Executive Office Building on the White House Campus on Dec. 12, 2023, in Washington. Joe Biden, 2023 President Joe Biden speaks during a funeral service for retired Supreme Court Justice Sandra Day O'Connor at the Washington National Cathedral on Dec. 19, 2023, in Washington. O'Connor, an Arizona native and the first woman to serve on the nation's highest court, died Dec. 1, 2023, at age 93. Joe Biden, 2024 President Joe Biden arrives to deliver remarks on the economy on June 28, 2023, at the Old Post Office in Chicago. Joe Biden, 2024 President Joe Biden, right, stands as an Army carry team moves the transfer case containing the remains of U.S. Army Sgt. Kennedy Ladon Sanders, 24, of Waycross, Ga., at Dover Air Force Base, Del., on Feb. 2, 2024. Sanders was killed in a drone attack in Jordan on Jan. 28, 2024. Joe Biden, 2024 President Joe Biden speaks during the State of the Union address on Capitol Hill on March 7, 2024, in Washington, as Vice President Kamala Harris and House Speaker Mike Johnson listen. Joe Biden, 2024 Vice President Kamala Harris embraces President Joe Biden after a speech on health care in Raleigh, N.C., on March. 26, 2024. Joe Biden, 2024 President Joe Biden greets Zion Schrode, 8 months, of Marin County, Calif., as he is held by his mother Erin Schrode during a Jewish American Heritage Month event, on May 20, 2024, in the Rose Garden of the White House in Washington. Joe Biden, 2024 Kansas City Chiefs coach Andy Reid, left, and CEO Clark Hunt, right, watch as President Joe Biden, center, puts on a Chiefs helmet during an event with the Super Bowl-champion Kansas City Chiefs on the South Lawn of the White House, on May 31, 2024, to celebrate their championship season and victory in Super Bowl LVIII. Joe Biden, 2024 President Joe Biden and first lady Jill Biden walk in the Normandy American Cemetery following a ceremony to mark the 80th anniversary of D-Day, on June 6, 2024, in Normandy. Joe Biden, 2024 U.S. President Joe Biden, right, greets Pope Francis ahead of a working session on Artificial Intelligence (AI), Energy, Africa-Mediterranean, on day two of the 50th G7 summit at Borgo Egnazia, southern Italy, on June 14, 2024. Joe Biden, 2024 President Joe Biden speaks during a campaign event with former President Barack Obama moderated by Jimmy Kimmel at the Peacock Theater on June 15, 2024, in Los Angeles. Joe Biden, 2024 President Joe Biden, right, and Republican presidential candidate former President Donald Trump, left, participate in a presidential debate hosted by CNN on June 27, 2024, in Atlanta. Joe Biden, 2024 First lady Jill Biden, President Joe Biden, Vice President Kamala Harris, and second gentleman Douglas Emhoff view the Independence Day firework display over the National Mall from the balcony of the White House, on July 4, 2024, in Washington. Joe Biden, 2024 President Joe Biden, right, and the Rev. Dr. J. Louis Felton pray at a church service at Mt. Airy Church of God in Christ on July 7, 2024, in Philadelphia. Joe Biden, 2024 President Joe Biden addresses the nation from the Oval Office of the White House in Washington on July 14, 2024, about the assassination attempt of Republican presidential candidate former President Donald Trump at a campaign rally in Pennsylvania. Joe Biden, 2024 President Joe Biden pauses as he speaks at the Biden campaign headquarters in Wilmington, Del., on Feb. 3, 2024. Joe Biden, 2024 President Joe Biden walks on stage to speak during the NAACP national convention July 16, 2024, in Las Vegas. Joe Biden, 2024 President Joe Biden walks between tombstones as he arrives to attend a mass at St. Joseph on the Brandywine Catholic Church in Wilmington, Del., on July 6, 2024. The poll of 1,251 adults was conducted Dec. 5-9, 2024, using a sample drawn from NORC's probability-based AmeriSpeak Panel, which is designed to be representative of the U.S. population. The margin of sampling error for adults overall is plus or minus 3.7 percentage points. Stay up-to-date on the latest in local and national government and political topics with our newsletter.

Sam Hicks, defense lead Abilene Christian over Northern Arizona 24-0 to extend 1st trip to playoffs

The incident serves as a reminder of the inherent risks associated with data centers and the importance of disaster preparedness and response strategies. Aliyun's transparent communication and rapid containment of the fire demonstrate their commitment to providing a secure and resilient cloud infrastructure for their clients.Stock market today: Wall Street hits records despite tariff talkHowever, CD Projekt Red's decision to silence Cockle on the topic of The Witcher 4 has cast a shadow of uncertainty over the future of the series. While the developer has not officially announced any plans for a new Witcher game, the warning issued to Geralt's voice actor suggests that there may be discussions or developments happening behind closed doors.